Raman Microscopy Imaging - Wide-field coherent anti-stokes raman scattering microscopy raws li picosecond supercontinuum qhov chaw

sij hawm22.03.04 Nws
leibKhoom

Abstract

Peb tawm tswv yim CARS microscope nrog kev pom dav dav raws li ntau txoj kev sib koom ua ke los tiv thaiv Stokes Raman scattering (CARS) excitation scheme.Los ntawm kev siv lub zog loj super txuas ntxiv tsim los ntawm thaj chaw loj-hom photonic siv lead ua fiber ntau (LMA PCF), ntau yam ntawm Raman tawg paj tuaj yeem ua rau muaj kev zoo siab rau thaj tsam dav.Lub CARS duab ntawm ib qho Raman tawg tawg kev co yog pom tau los ntawm kev siv cov lim bandpass sib raug.Cov txiaj ntsig kev sim qhia tau hais tias CARS nrawm nrawm tuaj yeem ua tiav ntawm cov qauv qauv siv lub zog siab picosecond supercontinuum pulse excitation thiab coj cov lim kom ua tiav qhov sib txawv Raman scattering band imaging.Cov tswv yim no tuaj yeem siv rau kev suav ntawm tes, kev ntsuas roj thiab lwm yam kev qhuab qhia biomedical uas xav tau kev ntsuas tus ncej siab, thiab nws tseem tau cog lus rau kev ntsuas kev kub ceev hyperspectral thaum ua ke nrog compressed sensing.

5-1

fig 1 (a) Schematic daim duab ntawm lub dav-tav coherent anti-Stokes Raman scattering (CARS) duab. (Lub koob yees duab: DHYANA 95, Tucsen)

5-2

Daim duab 2 Video-rate CARS duab ntawm PS thiab PMMA hlaws sib xyaw.

Kev tsom xam ntawm kev siv technology

Raws li Raman tawg teeb liab tsis muaj zog heev, lubTshooj 95Lub koob yees duab siv nyob rau hauv txoj kev tshawb no tau txais cov teeb pom kev zoo sCMOS nyias chip thev naus laus zis, uas tuaj yeem zam qhov cuam tshuam ntawm lub teeb los ntawm cov txheej txheem, txhim kho lub teeb pom kev zoo thiab txhim kho qhov hloov pauv photoelectric.Lub quantum efficiency yog mus txog 95%, thiab cov suab nrov nyeem tsuas yog 1.45 electrons (nce tus nqi).Nrog rau qhov dav spectral teb ntawm 200-1100nm thiab pixel loj ntawm 11μm, cov yam ntxwv no zoo haum rau cov ntawv thov no.Cov tswv yim no kuj tau cog lus tias yuav ua ke nrog compressed sensing kom ua tiav kev kub ceev hyperspectral duab yav tom ntej.

Kev siv qhov chaw

1. Shen, Y.;Wang, J.;Vaj, K.;Sokolov, AV;Scully, MO Wide-field coherent anti-stokes raman scattering microscopy raws li picosecond supercontinuum qhov chaw.APL Photonics 2018, 3, 116104, DOI: 10.1063/1.5045575

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